formulation and characterization of oral mucoadhesive chlorhexidine tablets using cordia myxa mucilage

Formulation and Characterization of Oral Mucoadhesive Chlorhexidine Tablets Using Cordia myxa Mucilage

BACKGROUND The dilution and rapid elimination of topically applied drugs due to the flushing action of saliva is a major difficulty in the effort to eradicate infections of oral cavity. Utilization a proper delivery system for incorporation of drugs has a major impact on drug delivery and such a system should be formulated for prolonged drug retention in oral cavity. OBJECTIVES The aim of the...

In Vitro Activity of Cordia myxa Mucilage Extract Against Leishmania major and L. infantum Promastigotes

1Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran 2Cellular and Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran 3Department of Dermatology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran 4Department of Pharmacy, Ahvaz Jundishapur University o...

Formulation Development of Oral Mucoadhesive Coated Terbutaline Sulphate Tablets Using Some Natural Materials Extracted from Edible Fruits Available in India

      Mucoadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of increasing the intimacy and duration of contact of drug with the absorbing membrane. Several synthetic polymers are in use for this purpose. Since the biodegradability of the synthetic polymers are questionable, in this investigation, an oral mucoadhesive controll...

Formulation and in Vitroevaluation of Glipizide Mucoadhesive Buccal Tablets

The aim of study was to prepare and characterize mucoadhesive buccal tablets of glipizide using different Mucoadhesive polymers such as Carbopol 940, Sodium alginate and HPMC K15M in combination. Twenty one formulation were developed with different concentration of mucoadhesive polymers in each formulation.The formulated buccal tablets were tested for surface pH,in vitro drug release and moistu...

Formulation, Characterization, in Vitro, in Vivo and Correlation Study of Mucoadhesive Sustained Release Tablets

Risperidone mucoadhesive buccal tablets: formulation design, optimization and evaluation

The aim of this study was to design and optimize risperidone (RIS) mucoadhesive buccal tablets for systemic delivery as an alternative route. Direct compression method was used for the preparation of buccal tablets, and screening studies were conducted with different polymers to determine their effects on tablet characteristics. Carbopol® (CP) and sodium alginate (SA) were selected as two polym...